This is one of the comparisons patients ask about most. Both products contain hyaluronic acid and both are injected — but what they do is quite different.
What dermal filler does
Standard dermal fillers contain cross-linked hyaluronic acid. Those links make the gel denser and keep it where it is placed. It is applied to a specific area and creates volume there: lips, chin, cheeks, jawline.
Filler is, in other words, a contouring tool. If you want to fill a depression, correct a profile or change a proportion, this is what you are looking for. The effect is immediate and lasts nine to eighteen months.
What Profhilo does
Profhilo adds no volume. It is a very high concentration of pure, non-cross-linked hyaluronic acid, delivered at defined points under the skin and spreading through the area. Its purpose is to hydrate from within and stimulate collagen and elastin production.
The result is not a change of shape but a change of texture: skin looks more hydrated, more elastic and brighter, and fine dehydration lines soften. The standard protocol is two sessions four weeks apart.
Which one fits you
A simple distinction helps: if you look in the mirror and think “this area has collapsed”, you are on the filler side; if you think “my skin looks tired”, you are on the Profhilo side.
In practice the two are often planned together. A measured amount of support at the cheek, for example, alongside a separate protocol for skin quality. That means working on two different layers — one volume, one texture.
Where skin is very thin, and in sensitive areas such as under the eyes, polynucleotide products like Rejuran are also considered. Which product suits is decided after skin analysis and facial assessment.
Both treatments are carried out by a clinician, with photographic records taken beforehand. The first consultation is free.
